These ultra low temperature systems can generate temperatures below 300 mK. He-3 gas is condensed by bringing it in contact with a He-4 reservoir (1 K pot). Ultra-low temperatures are achieved by reducing the vapour pressure on top of the liquid He-3 volume, using an internal sorption pump or an external pumping system.

Specific designs have been developed for a variety of optical and non-optical applications such as: Quantum Hall Effect, X-ray and Neutron studies, de Haas van Alphen measurements and studies of material surfaces that require cooling of Scanning Probe, Near Field Optical and Atomic Force Microscopes.

A sample can be placed in an environment of high and ultra high vacuum, He-3 exchange gas or LHe-3.